I play and coach basketball and usually wear a US12 or 13 for my previous running shoe, the Nike Pegasus. The materials feel durable and this should last quite a while for me.
I prefer my shoes to fit snugly and I can get that when I lace the MACH 4 tighter. Compared to my previous running shoes, these are reactive and bouncy, and I've been using them for hill sprints and daily runs.
Overall, this is a great shoe, and I haven't experienced any pain or discomfort that I'd usually get with other running shoes.